Key GPCR family receptors that are related to diseases. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or ...

该研究从进化、功能和结构角度，阐释了不同物种GPR4在质子感知中的共同机制以及物种特异性的独特机制，进一步描述了特定的质子感知GPCR是如何 ...

“When Heptares formed, we chose to focus on GPCRs because we knew that targeting these receptors leads to drugs,” says Matt Barnes, president and head of R&D at Nxera Pharma. GPCRs are ...

G protein-coupled receptors (GPCRs) are the largest group of membrane proteins. GPCRs' primary function is to convert a wide range of extracellular stimuli, including biogenic amines, peptides ...

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

The resulting images became the first known structure of ... "This could be the future of drugging adhesion GPCRs," Araç said. "The advantage of this is that extracellular regions are very ...