本研究首次揭示了耳念珠菌通过形成巨脂滴（gLDs）这一独特策略适应恶劣环境。gLDs 不仅作为脂质储存库，还通过调节细胞壁重塑、脂质代谢和线粒体功能，增强菌株对环境压力、抗真菌药物及宿主免疫防御的耐受性，从而促进其在医院环境中的传播和致病。研究还发现，gLDs 的形成与细胞内乙酰辅酶 A ...

本综述聚焦代谢与癌症的关联，探讨降糖药物（GLDs）如二甲双胍、罗格列酮、GLP-1 受体激动剂（GLP-1RAs）、SGLT-2 抑制剂等的抗癌潜力，涵盖作用机制、临床证据及联合疗法，为癌症治疗提供新思路。 代谢与癌症的关联为癌症治疗提供了新方向，降糖药物（GLDs ...

Service providers worldwide face challenges in managing increasingly complex network demands and customer billing GLDS’s comprehensive customer management and billing system is now integrated ...

This initiative will streamline and expand payment options for broadband service customers, and expand GLDS’ comprehensive suite of cloud-based, automated, customer management and provisioning ...

December 12, 2023) - Golden Spike Resources Corp. (CSE: GLDS) (OTCQB: GSPRF) (FSE: L5Y) ("Golden Spike" or the "Company") Further to its announcement on December 6, 2023, the Company has issued ...

(GLDS), the leading provider of billing, subscriber management and provisioning systems for small-to-medium global broadband providers, today announced it has completed integration between its ...

Previous research suggests that glucose-lowering drugs (GLDs), including GLP-1 receptor agonists and sodium-glucose cotransporter 2 (SGLT2) inhibitors, may offer a neuroprotective effect against ...