针对急性缺血性卒中(AIS)中氧化/亚硝化应激诱导的神经元死亡机制，大阪都立大学Hidemitsu Nakajima团队发现GAPDH（甘油醛-3-磷酸 ...

这项研究深入探究了5-HT在CD8+T细胞激活中的作用，提出了GAPDH的5-HT化修饰促进GAPDH胞内转移，增强糖酵解代谢，进而促进CD8+T细胞免疫活性的新机制。

2022年1月3日，中国科学院生物物理研究所陈畅课题组在Nitric Oxide上，在线发表了题为GAPDH S-nitrosation contributes to age-related sarcopenia through mediating apoptosis ...

本研究针对酵母细胞壁中缺乏信号肽的GAPDH（甘油醛-3-磷酸脱氢酶）非经典分泌机制展开探索，通过筛选基因缺失株并结合酶 ...

中国科学院生物物理研究所陈畅课题组在Nitric Oxide上，在线发表了题为GAPDH S-nitrosation contributes to 衰老性肌少症是随着衰老出现的骨骼肌力量和质量 ...

Figure 1: SNO–GAPDH interacts with SIRT1 near its nitrosylated Cys 150 residue. Mutational analysis identified Cys 387 and Cys 390, residues that are critical to SIRT1 function 14, as the sites ...

Stroke accounts for nearly 12% of all deaths worldwide, making it the second leading cause of death. In acute ischemic stroke, the ischemia and subsequent return of blood flow create oxidative and ...