Cholesterol gallstones occur when at least three simultaneous defects are present: (i) cholesterol supersaturation of bile with formation of cholesterol-rich unstable vesicles; (ii) accelerated ...

This has been made possible in the last few years by the cloning of a number of membrane transporters in hepatocytes and cholangiocytes that determine the formation of bile. [1] The discoveries ...

Although we often hear about ways to reduce blood cholesterol levels, cholesterol is one of many chemicals created and used by the body. Cholesterol is required for the formation of bile acids, which ...

Levels in bile were 2–3 times higher than in blood, indicating active secretion. Appreciable levels were found in the systemic circulation 24–48 hours after a single administration. Ingested FABACs ...