We investigated role of the folate–homocysteine metabolic pathway in the etiology of attention-deficit hyperactivity disorder (ADHD) due to its importance in maintaining DNA integrity as well as ...

Blocking the metabolism pathways that viruses rely on to replicate could be a new strategy for treating patients at an early time point," said Benjamin Gewurz, MD, Ph.D., of the Division of ...

Folate is a vitamin cofactor required as a one-carbon (1C) donor in multiple metabolic pathways. Its role is within the folate-mediated one-carbon metabolism (FOCM).

Regulation of the one carbon folate cycle as a shared metabolic signature of longevity. Nature Communications , 2021; 12 (1) DOI: 10.1038/s41467-021-23856-9 Cite This Page : ...

Folate is a vitamin cofactor required as a one-carbon (1C) donor in multiple metabolic pathways. Its role is within the folate-mediated one-carbon metabolism (FOCM).

Background: Capecitabine [Xeloda (XEL)] is an oral pro-drug of 5-fluorouracil, which in turn forms a terniary complex with thymidylate synthase and reduced folate. Folate metabolism could therefore ...

SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication. Nature Communications , 2021; 12 (1) DOI: 10.1038/s41467-021-21903-z Cite This Page : ...

Correlation of pharmacogenetic markers with docetaxel-based chemotherapy resistance in patients with advanced/metastatic non-small cell lung cancer. Background: Pemetrexed has been widely used in ...

SARS-CoV-2 hijacks two key metabolic pathways to rapidly replicate in host cells Blocking folate metabolism with oral, prophylactic drugs could reduce viral replication in infected cells ...

Technion researchers discover new pathway for attacking cancer cells ... findings that have been published in Cell Metabolism. The folate cycle is a process essential to DNA and RNA production.