We investigated role of the folate–homocysteine metabolic pathway in the etiology of attention-deficit hyperactivity disorder (ADHD) due to its importance in maintaining DNA integrity as well as ...

which inhibits the folate and the one-carbon metabolic pathways appropriated by the virus. The researchers also demonstrated that while intracellular glucose and folate are depleted in the SARS ...

Folate is a vitamin cofactor required as a one-carbon (1C) donor in multiple metabolic pathways. Its role is within the folate-mediated one-carbon metabolism (FOCM).

The main goal of this study was to evaluate the association between polymorphisms in the genes possibly involved in the metabolic pathways of pemetrexed and clinical outcome in NSCLC patients treated ...

Background: Capecitabine [Xeloda (XEL)] is an oral pro-drug of 5-fluorouracil, which in turn forms a terniary complex with thymidylate synthase and reduced folate. Folate metabolism could therefore ...

Regulation of the one carbon folate cycle as a shared metabolic signature of longevity. Nature Communications , 2021; 12 (1) DOI: 10.1038/s41467-021-23856-9 Cite This Page : ...

SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication. Nature Communications , 2021; 12 (1) DOI: 10.1038/s41467-021-21903-z Cite This Page : ...

Folate is a vitamin cofactor required as a one-carbon (1C) donor in multiple metabolic pathways. Its role is within the folate-mediated one-carbon metabolism (FOCM). This network of reactions ...

The findings, published in Nature Communications, highlight the potential therapeutic benefit of drugs such as methotrexate, which inhibit folate and one-carbon metabolic pathways appropriated by ...

Technion researchers discover new pathway for attacking cancer cells ... findings that have been published in Cell Metabolism. The folate cycle is a process essential to DNA and RNA production.