In enzymes, this can be achieved either by orbital ... is thermodynamically unfavorable, reduced flavin and pterin cofactors, as well as some metal centers, can effectively catalyze the reaction.

Enzymes play an important role in organic synthesis ... enzymatic site-selective chlorination of pyrrolic heterocycles by a flavin-dependent halogenase PrnC and apply it to the chemoenzymatic ...

The overarching goal of his research is to understand how enzymes control catalysis. The Stull lab primarily focuses on the class of enzymes that use riboflavin-derived cofactors (flavin-dependent ...

Its single-molecule sensitivity makes MFFMS a promising tool for drug discovery and development, particularly in targeting flavin-dependent enzymes and proteins. Understanding how drug candidates ...