Repair reactions involve the excision of chemically altered or mispaired bases from the DNA duplex. Resulting gaps are filled in by DNA polymerases; this reaction leaves a nick at or flanking the site ...

The role of the flanking DNA (sequences found on either side of the DNA fragment of interest) present around the recombinase ...

Transposable elements, or "jumping genes", were first identified by Barbara McClintock more than 50 years ago. Why are transposons so common in eukaryotes, and exactly what do they do? In addition ...

Mobile group II intron RNAs insert directly into DNA target sites before being reverse-transcribed by an intron-encoded protein. Target site recognition involves base-pairing between the RNA and DNA, ...