Endometrial cancer (EC) ranks as the second most prevalent gynecologic malignancy globally, with approximately 189,000 new ...

Lipid peroxidation adversely impacts the cellular repair system, particularly the ferroptosis suppressor protein 1 (FSP1), glutathione peroxidase 4 (GPX4) pathway, and GTP cyclohydrolase 1 (GCH1 ...

Various molecular pathways, such as glutathione peroxidase 4 (GPX4) inhibition, iron metabolism deregulation, and polyunsaturated fatty acid metabolism, converge to regulate ferroptosis.