Schematic hypothesis. Ischemic stroke causes iron accumulation, disrupting the redox balance, which in turn leads to two outcomes. One of the outcomes is the increased cell susceptibility to ...

Our findings unravel the intricate relationship between ferroptosis and necroptosis in stroke recovery. Iron stands out as a ...

A study has uncovered that iron orchestrates the activation of two damaging cell death pathways—ferroptosis and ...

A recent study has unveiled the pivotal role of Ferroptosis Suppressor Protein 1 (FSP1) in intervertebral disc degeneration (IDD), a primary cause of chronic lower back pain. Researchers ...

The schematic depicting a proposed model for the function of ferroptosis suppressor protein 1 (FSP1) in intervertebral disc degeneration. G ...

The intricate ubiquitin-proteasome system (UPS) plays a vital role in maintaining cellular homeostasis, determining the fate of apoptotic, autophagic, necroptotic, ferroptotic, and pyroptotic ...