This makes them more susceptible to a particular cell death pathway, ferroptosis," explains the researcher. "The mechanism appears to be universal. This means that it can be observed in all the ...

A study has uncovered that iron orchestrates the activation of two damaging cell death pathways—ferroptosis and ...

TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...

This suggests that FSP1 is a key mediator in the inflammatory pathway that drives disc degeneration. Surprisingly, although FSP1 is traditionally known as a ferroptosis suppressor, its involvement ...

A pivotal study has uncovered that iron orchestrates the activation of two damaging cell death pathways—ferroptosis and necroptosis—early in ischemic stroke recovery, exacerbating brain injury.

The schematic depicting a proposed model for the function of ferroptosis suppressor protein 1 (FSP1) in intervertebral disc degeneration. G ...