资讯

生物通1 年
追踪罕见的遗传疾病
研究揭示了FLVCR蛋白的动态结构及其在细胞内营养转运中的功能，研究结果可能用于开发治疗该基因突变引起的相应罕见病的疗法。 众所周知，FLVCR1和FLVCR2蛋白的功能障碍会导致人类罕见的遗传性疾病，导致运动、感觉和神经系统疾病。然而，这背后的生化机制 ...
生物谷1 年
Nature：揭示胆碱通过FLVCR2蛋白进入大脑机制
为了验证5:2禁食的影响，研究者在基于西式饮食的NASH小鼠模型中进行了试验，8周龄的小鼠在进食32周的富含糖和脂肪的西式饮食后，可诱导发生NASH ...
生物谷1 年
Sci Adv：KAT6A缺乏通过抑制RSPO2/Wnt信号通路损害认知功能
研究人员利用高功率低温电镜准确地看到了胆碱如何与FLVCR2结合。这对于了解如何设计模拟胆碱的药物，使其能够通过FLVCR2转运到达大脑内的作用 ...
Max Planck Society1 年
Tracking down rare hereditary diseases
FLVCR1 and FLVCR2 transport the cellular building blocks choline and ethanolamine The scientists have discovered that FLVCR 1 and FLVCR2 transport the molecules choline and ethanolamine across the ...
Healio14 年
FLVCR-like proteins may contribute to malaria control
For the study, researchers identified FLVCR-like proteins in a number of blood-feeding disease vectors and then went on to isolate anopheline orthologs of FLVCR from the two prevalent malaria ...
EurekAlert!14 年
UIC researcher unveils new approach to blocking malaria transmission
His abstract, "Anopheline Orthologs of the Human Erythroid Heme Exporter, FLVCR, Export Heme: Potential Targets to Inhibit Plasmodium Transmission," will be presented at the plenary session Sunday.
Science Daily14 年
New approach to blocking malaria transmission developed
Quigley presented the abstract "Anopheline Orthologs of the Human Erythroid Heme Exporter, FLVCR, Export Heme: Potential Targets to Inhibit Plasmodium Transmission," at the meeting. The research ...
Medical Xpress14 年
Researchers unveil new approach to blocking malaria transmission
Quigley spoke at a press briefing Saturday, Dec. 4. His abstract, "Anopheline Orthologs of the Human Erythroid Heme Exporter, FLVCR, Export Heme: Potential Targets to Inhibit Plasmodium ...
Medindia14 年
New Approach Towards Prevention of Malaria Transmission
Recent work has brought into light an advanced approach for inhibiting malaria transmission. The study, conducted by University of Illinois at Chicago researcher Dr. John Quigley, focuses on ...