shed light on the unique behaviour of extrachromosomal DNA (ecDNA), small, circular DNA structures that are common in some of the most difficult to treat cancers. The papers identify, for the ...

identify recurrent structural variant hotspots and find oncogene amplicons driven by extrachromosomal DNA. Most of the mutations accumulated in cancer cells are deleterious, and it is unclear how ...

Plasmids are extrachromosomal DNA sequences that are common to cells from all domains of life. Eren describes them as "typically small genetic entities that carry additional genes." They can be ...

Other oncology research teams are investigating the roles of extrachromosomal DNA, DNA damage responses and white blood cells called neutrophils in cancer.