Plasmids are extrachromosomal DNA sequences that are common to cells from all domains of life. Eren describes them as "typically small genetic entities that carry additional genes." They can be ...

Circular extrachromosomal DNA (ecDNA) is a form of oncogene amplification found across cancer types and is associated with ...

Other oncology research teams are investigating the roles of extrachromosomal DNA, DNA damage responses and white blood cells called neutrophils in cancer.

identify recurrent structural variant hotspots and find oncogene amplicons driven by extrachromosomal DNA. Most of the mutations accumulated in cancer cells are deleterious, and it is unclear how ...