Physiological extracellular matrix (ECM) calcification or mineralization is restricted to bones, teeth and the hypertrophic zone of growth plate cartilage. In contrast, pathological ECM ...

In an exciting advancement for dermatological science, researchers have uncovered the pivotal role of vitamin D and the enzyme CYP24A1 in the ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and emotional distress. These scars are driven by an overproduction of ...

Initiation of Phase 1/2 combination trial with PYX-201, an extracellular ADC targeting Extradomain-B Fibronectin (EDB+FN) and ...

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and emotional distress. These scars are driven by an overproduction of ...

Pyxis Oncology (PYXS) announced significant progress in its clinical program for PYX-201, a first-in-concept antibody-drug conjugate, ADC, that ...

Researchers have identified the key role of vitamin D and the enzyme CYP24A1 in keloid scar development, offering a promising new treatment approach.

Fibroblasts are the most common cell type in connective tissue. They can be compared to 'nature's stitches', holding together ...

Fibrosis stage is the result of the imbalance between synthesis and degradation of extracellular matrix components. Hepatic stellate cells are the major cell types involved in extracellular matrix ...