From the earliest studies with epithelial cells implanted into detrusor muscle to later experiments on smooth muscle in defined collagen gels, cell niche and extracellular matrix (ECM) have been ...

Our group has explored the regeneration of soft biological tissues through cell-extracellular matrix interactions, with a focus on collagen-rich environments and fibrosis. We have developed a new ...

The extensive extracellular matrix (ECM) of connective tissues is ... mediated by the transcription factor ATF6, which contains a basic leucine zipper domain. The release of BiP from the luminal ...

The extracellular matrix (ECM) is a complex network of secreted proteins that, beyond providing physical support to organs and tissues, regulates many cell functions, including proliferation, polarity ...

The extracellular matrix is a single component in a unique ... to external perturbations is an open question. "Yet, very basic physical processes could be key to understanding this complex space ...

This distinctive structure enables MFG-E8 to function as a molecular bridge, mediating cell-cell and cell-matrix interactions, promoting cell adhesion, remodelling the extracellular matrix (ECM ...