This construct was packaged into a replication defective adenoviral vector (Ad/5HRE-3NRSE) to determine neuron-selective and hypoxia-inducible gene expression in cultured mouse postmitotic primary ...

Wacker and Expression Manufacturing want to offer clients with an end-to-end, optimized solution for viral vector development and production.

The steps to create a stable, manufacturing cell line include host cell line selection, engineering of the expression vector, transfection, cloning and cell expansion, as well as various screening ...

The Baculovirus Expression Vector System (BEVS) is used to produce recombinant proteins. This is very useful in regards to virology studies and biotechnology applications. Baculovirus on ice ready ...

Retroviral vectors that are both non-replicating and non-integrating represent a novel and attractive tool that has potential advantages for gene delivery therapy, immunotherapy, and vaccinology.

In biopharmaceutical manufacturing, the development of an expression system that stably ... In brief, this process requires a vector containing the geneselect s) of interest to be transfected ...

This novel vector technology with its persistent payload expression offers certain advantages over other gene delivery systems (DNA, mRNA, viral) for transient protein expression and use in gene ...

An increase in serum choline levels to predict progression-free survival (PFS) in patients (pts) with advanced cancers receiving pembrolizumab. A phase I, dose-escalation study of ADG106, a fully ...

Data highlights advantages of single, non-replicative HSV-1 (nrHSV-1) vector hosting two transgenes with independent expression kineticsVectors also show high transduction rate of neurons in the CNS ...

Our vector technology uniquely enables the delivered RNA payload to be persistently expressed for days without integrating into the cellular genomes. This improves upon the persistence of nonviral ...