It reveals a pore complex with extended arms that could bind receptors involved in synaptic vesicle exocytosis ... a variety of neural and endocrine cells in all vertebrates (the venom contains ...

Understanding the complex interplay between membrane receptors and the exocytotic machinery remains a fundamental unresolved question in cell biology. Regulated exocytosis involves the fusion of ...

"Until our collaborative study, exocyst was understood to recognize and possibly tether secretory vesicles to the cell membrane, prior to exocytosis. In this study, we reveal biophysical studies ...