The variety of effects on E-cadherin expression (such as epithelial cell morphology, cell polarization, and growth inhibitory and tumor suppressive effects) is not solely the result of cell–cell ...

These models include humanized stem cell-derived in vitro systems that recreate the epithelial cell layer makeup and morphology. 2 Towards this end, scientists increasingly employ monolayer systems.

Human iPSCs forming a two-dimensional layer generate in vitro retinal pigment epithelial cells, which are pigmented and display typical cobblestone morphology. Hexagonal morphology and ...