Repressive epigenetic marks (such as DNA methylation, dimethylation of histone H3 at lysine 9 (H3K9me2) and H3K27me3) are dispensable for pre-implantation embryonic development and naive pluripotency.

In the current work, Zheng et al. established the role of an epigenetic mark derived from histamine — a monoamine molecule that modulates neuronal function — in neuronal signalling.

Nat. Rev. Mol. Cell Biol. 8, 983-994. Patel, D. J. and Wang, Z. (2013). A structural perspective of readout of epigenetic posttranslational modifications. Ann. Rev. Biochem. 82, 81-118. Readers of Kme ...

has used a combination of theoretical modeling and experimentation to elucidate the mechanisms that mediate the establishment of epigenetic marks following cell division. The findings, which ...

This is called “transgenerational epigenetic inheritance,” and it may explain how a person’s health and development could be influenced by the experiences of his or her parents and grandparents.

Lamarck's theory of acquired characteristics revisited through epigenetics in a groundbreaking study on cold-adapted rice ...

All chromosomes are stained red for DNA. By distinguishing between egg- and sperm-inherited chromosomes, researchers were able to track the effects of epigenetic marks carried by the sperm chromosomes ...

Reader of epigenetic marks could be 'game changer' for certain cancers Date: April 18, 2016 Source: University of Colorado Anschutz Medical Campus Summary: A new article outlines the essential ...

They are known as “epigenetic” marks since the changes are “on top of” the genome, not in the genome itself. What Dr Vallabh and her husband did was put a lock on the prion gene ...

There are more than 100 varieties of these chemical tags, collectively known as epigenetic marks. While they may help humans and other organisms respond to their environments, the tags can also ...

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells ...