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内毒素(Endotoxin)又称脂多糖(LPS),是革兰氏阴性细菌细胞壁中的一种成分。当细菌死亡溶解或采用人工方法破坏细菌细胞后,内毒素被释放到 ...
当你提取的质粒DNA是为了转染原代细胞、悬浮细胞或者敏感细胞;进行基因沉默研究、细胞注射显微操作;进行基因治疗或者DNA疫苗等要求极为严格的实验,就应该考虑Endotoxin-Free的质粒。 细菌内毒素是革兰氏阴性菌细胞壁上的一种脂多糖(LipopolySaccharide ...
The discovery of the host sensors — the Toll-like receptors — was rooted in chemical, biological and genetic analyses that centred on a bacterial poison, termed endotoxin. In all epochs and in ...
Bacteria can be found everywhere—even sometimes in clean rooms. That’s a problem for manufacturers of drugs and medical devices that are injected or implanted. Even if manufacturers can remove ...
Inadequate endotoxin testing places patients at risk. Knowing the relative strengths and weaknesses of available test methods is crucial to maintaining quality and safety. Endotoxins are small, ...
Endotoxin removal from a finished product is a major challenge for biopharmaceutical manufacturers; particularly as all endotoxin removal methods have operational limitations and may result in loss of ...
The levels of endotoxin in the bedding used by these children were examined in relation to clinical findings and to the cytokine-production profiles of peripheral-blood leukocytes that had been ...
Exposure to even tiny amounts can trigger a systemic—and potentially lethal—inflammatory response known as endotoxin shock. Proinflammatory SRTFs (stress-responsive transcription factors ...
Now it appears that the tide may be turning on endotoxin tests made from horseshoe crab blood—but it hasn’t gone out just yet. And it’s not used to test only products that go into humans.
What are the benefits of microfluidic automation? Microfluidic automation is the most straightforward available form of automation for endotoxin testing on the market today. It streamlines ...
Researchers from the University of Vienna found that consuming the artificial sweetener sucralose did not cause an increase in bacterial endotoxin levels in the body, compared to consuming sugar.
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