It is characterized by the accumulation of cholesteryl esters, macrophages, and fibrous elements in the intimal region underlying the endothelial-cell monolayer. The rupture of such lesions can ...

In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal ...

These endothelial abnormalities facilitated the accumulation and infiltration of monocytes and macrophages into the intima, where the macrophages exhibited both inflammatory and anti-inflammatory ...

Credit: Sumagin laboratory "This combination of a macrophage touch and endothelial cell activation and an induction of ICAM creates a hotspot for neutrophils to then migrate… so we think that ...

The newly identified progenitor cell, discovered in the outer layer of the aorta of adult mice, differentiates into endothelial cells and macrophages. The researchers thus dubbed it an ‘EndoMac ...

After activation by tenascin, macrophages produce various factors that induce the production of the cancer-promoting protein cocktail in endothelial cells. By eliminating macrophages or their ...

A specific subset of TAMs that produce a protein called Tie2 can also stimulate angiogenesis through secretion of vascular endothelial growth factor (VEGF) and other molecules (2). At the same time, ...

They found that macrophages in the choroid plexus secreted cathepsin S, which rose 10-fold from 2 to 24 months of age. This rise correlated with the fall in claudin 1. The authors confirmed that the ...