It is characterized by the accumulation of cholesteryl esters, macrophages, and fibrous elements in the intimal region underlying the endothelial-cell monolayer. The rupture of such lesions can ...

The enzyme arginase-II has an important role in cardiac aging, and blocking it could help hearts stay young longer.

Experimental and clinical studies suggest that there is an evolving role for endothelial progenitor cells in neoangiogenesis and rejuvenation of the endothelial monolayer. 6,12,17 The presence of ...

After activation by tenascin, macrophages produce various factors that induce the production of the cancer-promoting protein cocktail in endothelial cells. By eliminating macrophages or their ...

These endothelial abnormalities facilitated the accumulation and infiltration of monocytes and macrophages into the intima, where the macrophages exhibited both inflammatory and anti-inflammatory ...

Credit: Sumagin laboratory "This combination of a macrophage touch and endothelial cell activation and an induction of ICAM creates a hotspot for neutrophils to then migrate… so we think that ...

A specific subset of TAMs that produce a protein called Tie2 can also stimulate angiogenesis through secretion of vascular endothelial growth factor (VEGF) and other molecules (2). At the same time, ...