Purdue University scientists have discovered a key mechanism that regulates how plants develop chloroplasts, essential ...

The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

Our research group studies the mechanisms of protein trafficking and quality control at the endoplasmic reticulum (ER) in mammalian cells. A major focus of research is on the COPII protein machinery ...

Neurobiologists identify key protein Esyt linking calcium signaling to neurodegenerative diseases in cell membrane contact ...

The Jokitalo group studies structure-function interplay of organelles in mammalian cells. Our main model organelle is the endoplasmic reticulum. We employ a wide range of basic biological techniques ...

The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...