Nowhere is the interdisciplinary nature of cell biology better illustrated ... only that a better understanding of endocytosis is important to studies of membrane trafficking and protein targeting ...

By contrast, the bulk of endocytosis is often viewed as a constitutive process that ensures the continuous recycling of membrane components. In a recent paper (Mol. Cell 7, 421–432; 2001 ...

In our lab, we focus on clathrin-mediated endocytosis, the predominant route for membrane internalisation in most cells. In addition to its role in endocytosis, the clathrin machinery also forms ...

Previously, researchers suspected that the primary mechanism was fusion. During endocytosis, the target cell's membrane completely surrounds the extracellular vesicle, creating a kind of bubble ...

One key process to maintain this balance is endocytosis, the mechanism by which membrane components are internalised ... Leonardo is Assistant Professor of Cell Biology at HiLIFE and Faculty of ...

Living cells and tissues show a high capacity to absorb various chemical compounds from the surrounding environment. Although ...

These growth cues are received at the cell surface and are trafficked into the cell via a network of membrane-bound compartments called endosomes. However, we still do not understand the identity of ...