Deconvolution of this level, which we call the 'endocytic matrix', might uncover a fundamental aspect of how a cell is built. Here we summarize the current understanding of how endocytosis is ...

Once the endocytic vesicles are uncoated, they are capable of fusing with internal organelles, thereby delivering the cargo to the early endosome, where they are sorted to recycling endosomes that ...

"Chemical endocytic medicinal chemistry has the potential to impact every aspect of endocytic drugs from drug discovery and development to clinical practice," said Li. In this novel process ...

One key process to maintain this balance is endocytosis, the mechanism by which membrane components are internalised. Higher organisms have evolved a plethora of endocytic pathways with unique ...

But these researchers unveiled a new strategy called chemical endocytic medicinal chemistry that could change all of that, and even influence how the FDA evaluates future drugs, while helping ...

But these researchers unveiled a new strategy called chemical endocytic medicinal chemistry that could change all of that, and even influence how the FDA evaluates future drugs, while helping ...

But these researchers unveiled a new strategy called chemical endocytic medicinal chemistry that could change all of that, and even influence how the FDA evaluates future drugs, while helping ...

Endosomes are the integral parts of the endocytic process, and thereby, play crucial roles in various physiological processes, such as nutrient uptake, sorting and delivery of macromolecules ...

Scientists from Duke University School of Medicine, the University of Texas Health Science Center at San Antonio (UT Health San Antonio), and the University of Arkansas have found a way to improve ...

The strategy called chemical endocytic medicinal chemistry (CEMC) takes advantage of a natural process where cells "swallow" molecules called endocytosis. It could change the future of drug design ...