In the case of thalidomide, it was shown that one enantiomer was responsible for efficacy and another for side effects. Companies like Chiroscience (Slough, UK) and Sepracor based businesses on ...

Each of the mirror images of a molecule that is not superimposable is called an enantiomer. "In nature and in pharmacology there are multiple examples in which the two enantiomers have different ...

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The mechanism of antidepressant action of escitalopram, the S-enantiomer of racemic citalopram, is presumed to be linked to potentiation of serotonergic activity in the CNS resulting from its ...