Nor were there noteworthy differences when the patients <75 years were combined with 2083 patients >75 years similarly managed with either prasugrel 5 mg/day or standard clopidogrel. Roe said the ...

Based on pharmacokinetic data, the lower, 5-mg dose of prasugrel (Effient, Daiichi Sankyo/Eli Lilly) has been recommended for treatment of elderly patients to address the bleeding risks associated ...

Medindia neither buys nor sells drugs. Prasugrel (Prasurel (5 mg)) is a platelet aggregation inhibitor, prescribed for thrombotic cardiovascular (CV) events (life-threatening problems with the ...

"In addition, for those patients who weigh less than 132 pounds (60 kg), physicians should consider lowering the maintenance dose to 5 mg once daily. Patients taking Effient should also take 75 mg ...

which also included 2083 patients who were age 75 or older and who received either low-dose prasugrel (5 mg daily) or the standard clopidogrel dose. In a separate prespecified analysis ...

After a run-in period (5-21 days) in which all patients received aspirin alone, the low-weight group added prasugrel 5 mg daily, and the higher-weight group added prasugrel 10 mg daily, both for 12 ± ...

(3) A 5 mg maintenance dose should be used for patients who weigh less than 60 kg.(2) Prasugrel is generally not recommended for use in patients 75 years or older.(2) If, after a careful ...

In their study, the strategy of 1 month of aspirin 100 mg plus prasugrel 10 mg, followed by prasugrel 5 mg thereafter, was directly compared against the approach of aspirin 100 mg plus prasugrel ...

In a secondary analysis involving 2083 patients 75 years of age or older, we evaluated 5 mg of prasugrel versus 75 mg of clopidogrel. At a median follow-up of 17 months, the primary end point of ...

The results of the 4D-ACS trial – one-month DAPT followed by prasugrel 5 mg monotherapy in ACS patients who received a DCS – showed a reduction in NACE by 49%, driven in large part by a 77% ...

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Subjects received a single loading dose (LD) of prasugrel followed by once-daily maintenance dose (MD) for 10 d. They were enrolled into 3 groups: 60 mg LD/10 mg MD; 30 mg LD/7.5 mg MD ...