Plasma cell leukemia (PCL) is a rare disease that may present de novoor secondary to plasma cell myeloma. Advanced disease and extramedullary involvement are common clinical features at presentation.

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

Bortezomib (a proteasome inhibitor) has recently been approved for treatment of relapsed multiple myeloma, a plasma cell neoplasia ... standard treatment had no effect. Mice treated with ...

Multiple myeloma ... healthy stem cells first protects them from the damaging effects of the chemotherapy. After your stem cells are added back in, they can produce healthy plasma cells.

We do not know what causes MGUS. There may be a link to autoimmune diseases, genetics, or environmental factors. Like multiple myeloma, MGUS starts in a type of white blood cell called plasma cells.

Myeloma is a cancerous disorder of plasma cells that occurs primarily in patients in their forties and fifties, though younger patients are also at risk. The disease causes anemia, bone ...