Cutaneous reactions to metal implants, orthopedic or otherwise, are well documented in the literature. The first case of a dermatitis reaction over a stainless steel fracture plate was described ...

Dermatitis. 2006;17(3):109-122. In 1985, Maibach reported a series of trials performed to determine both the irritation and sensitization potential of clonidine and clonidine TTSs. The irritation ...