Kovar did not find E1A sequences in any of either the 27 Ewing tumor cell lines or the 19 primary Ewing tumors he examined. We have subsequently studied three Ewing tumor cell lines (RD-ES ...

Mien-Chie Hung, [5] of the Department of Molecular and Cellular Oncology, MD Anderson Cancer Center, Houston, Texas, talked about gene therapy strategies involving the adenovirus type 5 E1A protein.

The product of this tumor suppressor gene, a 105-kilodalton polypeptide ... The pRB polypeptide is also a major target of several DNA virus oncoproteins (adenovirus E1A, SV40 T antigen, and ...

Successful gene therapy treatment for cancer requires effective targeting of viruses that ... replication competent adenoviral vector in which expression of the essential E1A gene is regulated by ...

Given that wt p53 induces apoptosis in response to adenovirus E1a proteins 12 ... Levine, A.J. Adenovirus Elb-58kDa tumor antigen and SV40 large T antigen are physically associated with the ...

Background and Aim: Serum cancer antigen (CA) 125 elevation has been reported in patients with liver disease, but it is poorly characterized. The present study aimed to evaluate the range of serum ...