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此前研究提出,DOPA 脱羧酶(DOPA decarboxylase,DDC,也叫芳香族 L - 氨基酸脱羧酶 Aromatic - L - amino acid decarboxylase,AADC)可能是 LBDs 有前景的脑脊液(cerebrospinal fluid,CSF)生物标志物,不过血浆 DDC 水平的研究结果却不一致,这使得血浆 DDC 作为 LBDs 潜在生物标志物 ...
Dopa decarboxylase, an enzyme involved in the synthesis of the neurotransmitter dopamine, catalyses the formation of functional dopamine through decarboxylation of a precursor tyrosine derivative.
2023年9月18日,卡罗林斯卡学院和隆德大学的研究人员在 Nature 子刊 Nature Aging 上发表了题为:DOPA decarboxylase is an emerging biomarker for Parkinsonian disorders ...
In participants who had Parkinson’s disease or DLB, the cerebrospinal fluid had much higher levels of DOPA decarboxylase – an enzyme that helps with the production of dopamine – compared ...
The marker in question is called DOPA decarboxylase (DCC). In the current study, DCC was found to be elevated in individuals with Parkinson's disease as well as in people with other diseases that ...
Anil Modak, PhD, of Cambridge Isotopes Laboratories, in Andover, Massachusetts, reported early feasibility data using the test, which uses measures of dopa decarboxylase enzyme activity in PD ...
For this study, Gregg and his colleagues focused on a gene called dopa decarboxylase, which neurons need to manufacture dopamine, serotonin and noradrenaline. These are all neurotransmitters ...
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