Blocking this mechanism results in higher serum potassium levels. In states of hypokalemia, or low potassium, digoxin toxicity is actually worsened because digoxin normally binds to the ATPase ...

Digoxin can cause many different ECG abnormalities when supratherapeutic levels occur. The classic digoxin effect appears as a downsloping ST segment depression, also known as the "reverse tick ...

Toxicity risk increased by hypokalemia, hypomagnesemia, hypercalcemia, diabetes. Hypocalcemia may nullify effects. Thyroid disease. Hypermetabolic states. Monitor digoxin levels, electrolytes ...