What is Differin? Differin is an acne-fighting gel that contains 0.1% adapalene — a powerful, prescription-strength retinoid that targets blackheads and whiteheads and prevents future blemishes.

However, according to Dr. Ariel Ostad, a cosmetic surgeon based in New York City, products that use a prescription-strength retinoid called adapalene are outliers in this pricey OTC mark-up.

Clear your pores with the best blackhead treatments in 2025. Shop cleansers, serums, strips and more and learn how to remove ...

Clear your pores with the best blackhead treatments in 2025. Shop cleansers, serums, strips and more and learn how to remove ...

However, the significance of these findings with regard to the mechanism of action of adapalene for the treatment of acne is unknown. Discontinue if allergic or anaphylactic reactions occur.

When it comes to acne, nowhere on your body is safe — breakouts can appear on your scalp or hairline, felt, but not seen. As its name suggests, scalp acne consists of whiteheads and blemishes ...