Cholestatic liver diseases, including primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), are conditions characterized by impaired bile flow, leading to liver damage and ...

However, disruptions in bile acid metabolism can lead to cholestatic liver diseases, where bile flow is impaired, resulting in the accumulation of bile acids in the liver and bloodstream.

with particular focus on the implications of using livers from donors with detectable HBV seromarkers, as well as on the diagnosis and treatment of fibrosing cholestatic hepatitis.