Figure 1: Systemic increase in Flt3l amounts, Flt3-dependent bone marrow activation and dendritic cell expansion during P. chabaudi infection. Figure 2: Role of Flt3l-responsive CD8-α + langerin ...

Fms-like tyrosine kinase-3 ligand (Flt3L) uniquely binds the ... stem cells (HSCs), early progenitor cells, immature thymocytes and steady-state dendritic cells (DCs) and induces their ...

Oncolytic viruses trigger immunogenic cell death in tumors, releasing signals that activate innate immune cells and promote tumor-specific T-cell responses. While some oncolytic viruses, including FDA ...

such as dendritic cells (DCs), are essential for effective T cell responses,” explained Dr. Fling. “Flt3 [fms-like tyrosine kinase 3] ligand, a growth factor for DCs, was discovered ~27 years ago at ...