This data indicates that the phenotype of dermal fibroblasts from the deeper layers resemble those from HTS and strongly suggests that deep dermal fibroblasts may play a critical role in HTS.

Researchers found limited evidence that repetitive application of sunscreen with titanium dioxide provides a layer of deep dermal penetration, but suggest that further studies are needed ...

It is a non-invasive laser that uses technology to gently go past the surface skin layers and gently heat the deep dermal layer by distributing laser energy over thousands of micro pulses.