the inter-relationship between DNA replication and nuclear structure, and the temporal order of replication. A topic conspicuously missing from this section is establishment of sister chromatid ...

But James Watson and Francis Crick's claim was a valid one, for they had in fact discovered the structure of DNA, the chemical that encodes instructions for building and replicating almost all ...

Scientists at the University of Iowa have made an exciting discovery that could lead to new cancer-fighting drugs. They found ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...

The double ring, spool-like structure of RAD52 protects replicating DNA in dividing cells. A study led by the University of ...

RAD52 has already shown promise as a drug target. Inhibitors of the protein can selectively kill cancerous cells while ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

We employ fully reconstituted yeast and human DNA replication systems to investigate the structure and biochemical mechanism of the eukaryotic replication machinery. A particular focus of the lab is ...

When organisms encounter problems -- what scientists call "replication stress ... bases (represented by G in the DNA code) can fold into a DNA structure called a G-quadruplex, or G4 for ...

"The replication process is carried out ... G-quadruplex–stalled eukaryotic replisome structure reveals helical inchworm DNA translocation, Science (2025). DOI: 10.1126/science.adt1978 ...

The flowerpot snake, one of the world's smallest snakes, has some unusual distinctions. Also known as the Brahminy blind ...