Maintaining the chemical integrity of DNA in the face of assault by oxidizing agents is a constant challenge for living organisms. Base-excision repair has an important role in preventing ...

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

Vital for DNA repair is the methylation of the histone protein, H3, at lysine-4 by SETD1A, a new study finds. This methylation promotes the accumulation of a protein called RIF1 at sites of DNA ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

Please use one of the following formats to cite this article in your essay, paper or report: APA. Smith, Yolanda. (2023, July 19). DNA Replication and Repair.

Inherited mutations in DNA-repair genes such as BRCA2 are associated with increased risks of lethal prostate cancer. ... age, or any knowledge of genetic background.

These proteins repair DNA damage from UV radiation using light. “They’re very good at using almost every single photon they catch,” says Thomas Lane at the German Electron Synchrotron (DESY).

, have, for the first time, been able to view how this repair machinery prioritizes fixing these thousands of instances of DNA damage. They achieved this feat using their novel sequencing technique, ...

On Earth, the body can repair double-strand breaks by adding and deleting DNA bases, or re-joining the two pieces without altering them. Before the Genes In Space-6 experiment, however, these ...