As our bodies grow, cells proliferate to form tissues, and cells frequently have to be repaired or replaced throughout life..

New research illustrates how a DNA repair protein suppresses senescent cells, reducing age-associated chronic inflammation.

Ultraviolet (UV) radiation is known to cause DNA damage, and while that damage may accumulate and eventually lead to diseases ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...

They are formed in a woman's body before birth and have to be on standby for decades to possibly be fertilized one day. But as they age, they accumulate more and more DNA damage. Until now, it has ...

Sunburns and aging skin are obvious effects of exposure to harmful UV rays, tobacco smoke and other carcinogens. But the effects aren't just skin deep. Inside the body, DNA is literally being torn ...

Scientists at Scripps Research have now captured the first detailed images of the DNA repair protein, Pol-theta, in action, revealing the molecular processes responsible for a range of cancers.

New findings show that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the senescence-associated secretory phenotype (SASP), which causes zombie-like ...

p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...

New research uncovers new insights into preventing chronic inflammation caused by aging-related zombie-like cells. In humans ...