In the first step, repressor molecules induced by differentiation cues bind to the gene promoter region and turn off transcription. This form of repression seems to be completely reversible once ...

Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

A new study published in PLOS Genetics has identified an extreme mutational hotspot within the genome of Pseudomonas ...

DNA is well-known for its double helix shape ... "We also found that i-motifs form in the promoter region of oncogenes, for instance the MYC oncogene, which encodes one of cancer's most notorious ...