Diane Gershon takes a closer look at what's on offer. Over the past decade, DNA microarrays have emerged as an important tool for monitoring the expression of genes in a highly parallel fashion ...

While DNA microarrays are the most common, there is increasing utilization of protein, peptide and glycan microarrays. Structure of a DNA microarray Samples are arranged on the array in spots of ...

DNA microarray (gene chip, DNA chip, or biochip) is one such technology that either measures DNA or uses DNA as a part of its detection system. In each of the spots in this array, a known DNA ...

Based on electrostatic repulsion that yields images visible to the naked eye, the technique could revolutionize the use of DNA microarrays for both research and diagnostics. The dream of ...

One way they do this is to use a DNA microarray to determine the expression levels of genes. When a gene is expressed in a cell, it generates messenger RNA (mRNA). Overexpressed genes generate ...

Because of their huge scanning capability, DNA microarrays can drive R&D programs that would have been impossible before the advent of this technology. Southern blotting, now over three decades ...

We have assessed three quantitative gene expression measurement technologies for their performance metrics, correlated the results obtained with them to DNA microarray data and then subsequently ...

Chips containing orderly arrays of thousands of DNA sequences--so-called DNA microarrays--have become an indispensable part of the biologist's tool kit for studying gene expression and gene mapping.

Central to microarray analysis for determining gene expression is the hybridization of fluorescently labeled RNA with a short strand of complementary DNA that is tethered to a solid surface ...

DNA microarray analysis is an effective method to detect unintended effects by detecting differentially expressed genes (DEG) in safety assessment of genetically modified (GM) crops. With the aim to ...

“We believe this technique could revolutionize the use of DNA microarrays for both research and diagnostics.” Groves, who is also a Howard Hughes Medical Institute (HHMI) investigator, and members of ...