首先，研究人员在体外使用IFNαA+CD40 Ab刺激BMDC模拟体内DC与CD4+T细胞之间的刺激信号，RNA-seq揭示一部分基因在IFNαA+CD40 Ab刺激时显著增加，称之为“扩 ...

The protective efficacy of Ad-hTRP2-transduced DC clearly depended on the presence of CD4 + T helper cells. Furthermore, AD-hTRP2-transduced DC, but not direct injection of Ad-hTRP2, were ...

为探究宿主效应 CD4 + T 细胞能否被过继转移的 CD8 + T 细胞激活，研究人员开展了相关研究。结果发现小鼠肿瘤特异性 Tc9 细胞可招募并激活宿主效应 CD4 + T 细胞控制抗原缺失复发肿瘤。该研究揭示了体内激活肿瘤特异性 CD4 + T 细胞的机制。 宿主效应 CD4 + T 细胞是 ...

Louis M. Weiner, MD, director of the Lombardi Comprehensive Cancer Center at Georgetown University, in Washington, DC, indicated that in contrast with CAR T-cells, these CD4 T-cells target ...

The relationship between the timing of the initiation of antiretroviral therapy (ART) after infection with human immunodeficiency virus type 1 (HIV-1) and the recovery of CD4+ T-cell counts is ...