Diseases such as covid-19 and influenza can be fatal due to an overreaction of the body’s immune system called a cytokine storm. Cytokines are small proteins released by many different cells in ...

rather than what's actually being produced," says Fred Finkelman of the University of Cincinnati. So many scientists measure cytokine protein directly instead. Using as their key reagents an ...

T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...

The deal comes just a few days after Synthekine secured approval to start clinical trials in the US of its lead drug candidate STK-012, a partial agonist of the cytokine IL-2 that is being ...

Although still preliminary, the involvement of cytokine signalling loops in pre-malignant cell-fate decisions, as well as the defects in cytokine-receptor modules seen in later stages of cancer ...

Siltuximab effectively treated patients who experienced common adverse events after chimeric antigen receptor T-cell therapy, ...

A recent study has unveiled the pivotal role of Ferroptosis Suppressor Protein 1 (FSP1) in intervertebral disc degeneration ...

Their findings show that these cells greatly increase in number when exposed to the cytokine interferon- (IFN ), presenting a promising target for therapeutic strategies. Researchers from the ...

Interim analysis of overall survival in potentially registrational phase 3 ARTISTRY-7 trial in platinum-resistant ovarian cancer expected in late ...

“We are thrilled to welcome these industry-leading experts to our Clinical and Scientific Advisory Board,” said Dr. Nicole K. Paulk, CEO, Founder, and President of Siren Biotechnology. “Their deep ...

Dr. Deepa Jagadeesh discusses Ordspono's potential FDA approval for relapsed/refractory follicular lymphoma, highlighting its manageable toxicity and low CRS rate.