Compared with intermittent cyclophosphamide, daily oral MMF front-loads intense immunosuppressive therapy at a time when the disease is most active. At our institution, patients with severe lupus ...
Recent evidence indicates that cyclophosphamide exposure increases the risk of hematologic malignancies in patients with rheumatoid arthritis. In a large administrative database cohort of patients ...
In contrast to current nonspecific immunosuppressive agents, the emergence of immunomodulatory drugs provides the possibility of interfering with specific pathogenic pathways. Novel targeted ...