Cyclophosphamide, a DNA-alkylating agent, induces non-apoptotic cell death of tumour cells and T cells. In addition, it can deplete regulatory T cells, thereby overriding their antitumour immune ...

Cyclophosphamide was discontinued after 2 ... and positivity for antinuclear antibodies and antibodies to double-stranded DNA. During the index hospitalization, the patient's medications included ...