Cyclin-dependent kinases (CDKs ... kinases lack at least one of the conserved catalytic residues 2 and may not have kinase activity. Kinase activity has not been detected for several CDK-related ...

p27 (also known as KIP1, and encoded by CDKN1B) is regulated by multiple signal transduction pathways in normal and malignant cells. CDKN1B transcription can be regulated by the FoxO family and ...

An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.