See Box 1 for location preferences of known enhancer sequences. From a comparative point of view, two tracks are particularly useful. The first is the “Conservation” track (shown in Fig.

“We didn’t think it would work.” The results serve as an extreme example of what scientists are now recognizing as trends among enhancers—that activity can be conserved over long evolutionary ...

Whole genome comparisons between species that are either closely related or more phylogenetically separated—such as human, mouse, and dog—have revealed a subset of sequences that neither code for ...