whereas the latter encode concentrative nucleoside transporters (CNTs), which are sodium-coupled and show high affinity for substrates with variable selectivity. These proteins are expressed in ...

这种称之为富集型核背转运蛋白(concentrative nucleoside transporter, CNT)的转运分子主要功能是将DNA及RNA的组成元件——核苷从细胞外转运至细胞内。它还能够将核苷样的药物转运通过细胞膜。一旦进入到细胞内，这些核苷样药物就会被修饰成核苷掺入到DNA链中 ...

we undertook a comprehensive genetic and functional analysis of variation in the coding region of the human concentrative nucleoside transporter, CNT3, encoded by SLC28A3. Population genetic ...

Scientists have modeled all of the steps by which nucleosides and their analogs are transported into cells by a specific molecule named the concentrative nucleoside transporter or CNT. The finding ...