Complement deficiencies affecting the classical pathway—genetically determined or acquired as a result of complement component consumption—are strongly associated with an increased risk of SLE ...

The complement cascade, a key regulator of innate immunity, is a rich source of potential therapeutic targets for diseases including autoimmune, inflammatory and degenerative disorders. Morgan and ...

Healthy immune function is important to protect the body from disease and infections. These proteins, which are part of the complement system, help destroy harmful invaders, such as bacteria and ...

The global Complement Deficiency Tests market size was valued at USD 210.6 Million in 2021 and is expected to expand at a CAGR of 7.6% during the forecast period, reaching USD 326.88 Million by 2027.

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Complement or insult: the emerging link between complement cascade deficiencies and pathology of myeloid malignancies, Journal of Leukocyte Biology, 116, 5, (966-984), ...

CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy (the CHAPLE syndrome) is caused by abnormal complement activation due to biallelic loss ...

If your complement components are normal but your C3 complement levels are low, you have an inherited component C3 deficiency. If a person inherits component deficiency, they are more likely to ...

Terminal complement deficiency is also associated with an increased risk of disseminated infection owing to Neisseria gonorrhoeae; health care providers should inform patients who are receiving ...

Increasing prevalence of chronic diseases further expected to drive the growth of the complement-targeted therapeutics market. Whereas, large proportion of population living with complement deficiency ...